- Mouse Anti-AKT1 Antibody
- MyBioSource.com
- Pricing InfoSupplier PageView Company Product Page
- MBS4380872
- 0.02 mg (With BSA & Azide at 0.2mg/ml)
- Monoclonal
- Human, Mouse
- 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml
- Western Blot (WB), Immunohistochemistry (IHC) Paraffin
- Mouse
- 62kDa
- AKT1
- Purified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
- AKT serine/threonine kinase 1
- RAC, RAC-ALPHA, CWS6, PRKBA, AKT, PKB, PKB-ALPHA
- Unconjugated
- IgG
- AKT1/2784
Specifications/Features
Recognizes a protein of 62kDa, which is identified as AKT1. The serine/threonine kinase Akt family contains several members, including Akt1 (also designated PKB or RacPK), Akt2 (also designated PKB tyrosine residues 740 and 751, which bind the subunit of the phosphatidylinositol 3-kinase (PI 3-kinase) complex. Activation of Akt1 by insulin or insulin-growth factor-1 (IGF-1) results in phosphorylation of both Thr 308 and Ser 473. Akt proteins become phosphorylated and activated in insulin/IGF-1-stimulated cells by an upstream kinase(s), and the activation of Akt1 and Akt2 is inhibited by the PI kinase inhibitor wortmannin